Anat Rec (Hoboken), 2012 · DOI: 10.1002/ar.22537 · Published: October 1, 2012
This study compares the tissues of original and regenerated lizard tails to understand regeneration. It provides baseline data for future research. The regenerated tail has a cartilage tube enclosing a spinal cord with an ependymal core, but lacks dorsal root ganglia and peripheral nerves regeneration. The muscles in the regenerated tail are disorganized with more connective tissue compared to the original tail.
Provides a framework for future studies on lizard tail regeneration, potentially informing mammalian regeneration research.
The structural differences between original and regenerated tails provide a basis for biomechanical studies to understand functional capabilities and limitations.
The differences in nerve regeneration can inform neuromuscular assays to understand the functional capabilities of the regenerated tail.