Abundance in proteins expressed after functional electrical stimulation cycling or arm cycling ergometry training in persons with chronic spinal cord injury

This study investigates how different types of exercise affect protein levels in muscles of men with spinal cord injuries. Specifically, it looks at proteins involved in energy use and glucose metabolism. The researchers compared functional electrical stimulation (FES) cycling of paralyzed legs to arm cycling, measuring changes in proteins in both paralyzed and non-paralyzed muscles. The findings suggest that both types of exercise can increase the abundance of key proteins in the trained muscles, potentially improving glucose utilization and energy regulation.

• 1
  FES-LEC training led to a 3.8-fold increase in GLUT-4 protein expression in the vastus lateralis muscle.
• 2
  ACE training resulted in a 3.8-fold increase in PGC-1α protein expression in the triceps muscle.
• 3
  Both FES-LEC and ACE training were associated with increased AMPK protein expression in the trained muscles.