Antibiogram data of urinary tract infection in spinal cord injury patients in an outpatient setting

Neurosciences, 2024 · DOI: 10.17712/nsj.2024.1.20230063 · Published: January 1, 2024

Spinal Cord Injury Immunology Healthcare

Simple Explanation

This study focuses on urinary tract infections (UTIs) in patients with spinal cord injuries (SCI), a common issue due to bladder dysfunction and catheter use. The research aims to identify the most common bacteria causing UTIs in SCI patients, depending on how they manage their bladder (voiding method), and which antibiotics are most effective against these bacteria. The goal is to provide doctors with data to help them choose the right antibiotics for treating UTIs in SCI patients, reducing antibiotic resistance and improving treatment outcomes.

Study Duration

2008 to 2019

Participants

151 SCI patients with UTI

Evidence Level

Observational cross-sectional study

Key Findings

1
E. coli was found to be the most common cause of UTIs overall, especially in patients using self-intermittent catheterization (SIC) and indwelling catheters (IDC).
2
Proteus mirabilis was frequently found in patients using suprapubic catheters (SPC).
3
The antibiotic gentamicin showed the highest overall sensitivity, while nitrofurantoin was the most effective oral antibiotic.

Research Summary

This study analyzed urine culture results from 151 SCI patients with UTIs to determine common causative organisms and their antibiotic sensitivities based on different voiding methods. The most common organism was E. coli, particularly in patients using SIC and IDC, while P. mirabilis was more frequent in SPC users. Gentamicin and nitrofurantoin showed the highest sensitivity. The study highlights the increasing resistance to ciprofloxacin and emphasizes the need for local antibiograms to guide empirical antibiotic treatment in SCI patients with UTIs.

Practical Implications

Empirical Treatment Guidance

The antibiogram data can assist clinicians in selecting appropriate empirical antibiotic therapy for UTIs in SCI patients, potentially reducing treatment failures and antibiotic resistance.

Voiding Method Education

The study highlights a high preference for Foley catheters, suggesting a need for increased patient education on safer voiding methods to minimize long-term complications.

Further Research

The variations in causative organisms and antibiotic sensitivities compared to other studies emphasize the need for multi-center studies to establish national antibiograms for SCI patients.

Antibiogram data of urinary tract infection in spinal cord injury patients in an outpatient setting

Simple Explanation

Key Findings

Research Summary

Practical Implications

Empirical Treatment Guidance

Voiding Method Education

Further Research

Study Limitations

Your Feedback

Was this summary helpful?

Antibiogram data of urinary tract infection in spinal cord injury patients in an outpatient setting

Simple Explanation

Key Findings

Research Summary

Practical Implications

Empirical Treatment Guidance

Voiding Method Education

Further Research

Study Limitations

Your Feedback

Was this summary helpful?