Comparison of different antibiotic protocols for asymptomatic bacteriuria in patients with neurogenic bladder treated with botulinum toxin A

This study looks at whether giving antibiotics to patients with spinal cord injuries before they get botulinum toxin A injections into their bladder helps prevent urinary tract infections (UTIs). These injections treat bladder problems caused by nerve damage. The study examined different ways of using antibiotics, including giving them for several days, three days, or just a single dose, to see which method was best at preventing UTIs. The results suggest that a single dose of antibiotics before the injection might be enough to prevent UTIs, which could help reduce the overuse of antibiotics and the development of antibiotic-resistant bacteria.

• 1
  The study found a low overall rate of symptomatic UTIs (1.8%) among patients receiving botulinum toxin A injections for neurogenic bladder.
• 2
  There was a trend toward a higher rate of UTIs in the group that received antibiotics for more than three days, compared to those who received a single dose or three days of antibiotics.
• 3
  The use of indwelling urethral catheters (IUCs) was more common in the group that received antibiotics for more than three days, which may have contributed to the higher UTI rate in this group.