Contrast-medium injury of spinal cord after cerebral angiography using nonionic contrast agents: A case report and literature review

This case report describes a rare complication following cerebral angiography called contrast-induced spinal cord injury (CIS). The patient, a 41-year-old male, developed quadriplegia after undergoing the procedure. The doctors initially suspected contrast-induced encephalopathy (CIE) due to the patient's symptoms and imaging findings. However, the later development of paralysis and further MRI scans revealed CIS. The patient was treated with medications and rehabilitation, which led to improvement in his neurological symptoms. This case highlights the importance of considering CIS even when using modern contrast agents.

• 1
  A patient developed contrast-induced spinal cord injury (CIS) following cerebral angiography using a nonionic contrast agent (Ioversol). This is a rare occurrence, as CIS is more commonly associated with ionic contrast agents.
• 2
  The patient initially presented with symptoms of contrast-induced encephalopathy (CIE), which resolved, but later developed quadriplegia and paresthesia, leading to the diagnosis of CIS.
• 3
  MRI findings revealed a hyperintense signal in the spinal cord, supporting the diagnosis of CIS. The patient's condition improved with treatment including methylprednisolone and rehabilitation.