Eur Spine J, 2008 · DOI: 10.1007/s00586-008-0708-8 · Published: July 18, 2008
This study examines the effectiveness and cost of percutaneous vertebroplasty (PVT) compared to conservative medical therapy (CMT) for treating osteoporotic vertebral fractures. Patients with refractory pain were offered either PVT or CMT. The study then measured pain levels, mobility, and activities of daily living after both treatments. The results indicated that PVT was initially more effective in reducing pain and improving function, but over 12 months, the differences between the two treatments became less significant.
PVT may be considered as a first-line treatment for patients with acute osteoporotic vertebral fractures and refractory pain.
While PVT demonstrates higher initial cost-effectiveness, long-term benefits may not justify the higher cost compared to CMT.
The findings suggest a need for individualized treatment plans considering both clinical effectiveness and economic factors.