Effectiveness of two vitamin D3 repletion protocols on the vitamin D status of adults with a recent spinal cord injury undergoing inpatient rehabilitation: a prospective case series

This study looked at how well two different amounts of vitamin D3 supplements improved vitamin D levels in adults who had recently experienced a spinal cord injury (SCI) and were in the hospital for rehabilitation. One group received a higher dose (10,000 IU weekly plus 1000 IU daily), while the other received a lower dose (1000 IU daily). The study found that while both amounts increased vitamin D levels, neither was very effective in bringing most people up to a sufficient level during their time in the rehabilitation center.

• 1
  Both vitamin D3 protocols increased serum 25OHD levels, with the higher dose regimen showing a greater increase compared to the lower dose regimen.
• 2
  None of the participants on the higher dose regimen remained vitamin D deficient, but only one achieved vitamin D sufficiency.
• 3
  Nearly all individuals on the lower dose regimen remained vitamin D insufficient, with only two reaching vitamin D sufficiency.