F1000Research, 2022 · DOI: https://doi.org/10.12688/f1000research.52670.2 · Published: March 7, 2022
This study explores a new rehabilitation approach for individuals with spinal cord injuries (SCI) that uses remote ischemic conditioning (RIC) to improve hand function. RIC involves briefly restricting blood flow to an arm to potentially enhance neuroplasticity, the brain's ability to reorganize itself. The study will measure changes in corticospinal excitability, pinch force, and inflammatory biomarkers to understand how RIC affects hand function.
If RIC demonstrates a beneficial effect on neuroplasticity, it could be easily coupled with rehabilitation training in clinical or home settings to improve hand function in individuals with cervical SCI.
The study will provide preliminary information regarding the mechanism by which RIC promotes neuroplasticity and improves functional training effects through analysis of neurophysiology and inflammatory mediators.
The findings will inform future studies testing RIC coupled with various other rehabilitation interventions to enhance long-term functional movements in people with cervical spinal cord injury.