Epidural Spinal Cord Stimulation of Lumbosacral Networks Modulates Arterial Blood Pressure in Individuals With Spinal Cord Injury-Induced Cardiovascular Deficits

Spinal cord injury often leads to low blood pressure and difficulty tolerating upright positions. This study explores whether epidural stimulation of the spinal cord can help regulate blood pressure in individuals with spinal cord injury. The study involved applying electrical stimulation to the lower spinal cord in individuals with spinal cord injuries and monitoring their blood pressure and muscle activity. The findings suggest that spinal cord stimulation can increase blood pressure in those with cardiovascular deficits due to spinal cord injury, potentially improving their ability to stand and participate in rehabilitation.

• 1
  Spinal cord stimulation increased arterial blood pressure in individuals with SCI-induced cardiovascular deficits.
• 2
  In participants without cardiovascular deficits, spinal cord stimulation did not induce significant increases in arterial blood pressure.
• 3
  During standing assisted by spinal cord stimulation, blood pressure was maintained in individuals with cardiovascular deficits.