Evaluation of 3 Methods of Bladder Irrigation to Treat Bacteriuria in Persons With Neurogenic Bladder

The study aimed to determine if bladder irrigation with saline, acetic acid, or neomycin-polymyxin could reduce bacteriuria in people with neurogenic bladder who use catheters. Participants irrigated their bladders twice daily for 8 weeks, and researchers checked their urine for bacteria levels, pH, and antibiotic resistance. The study found that none of the irrigation solutions significantly reduced bacteria levels or inflammation in the bladder.

• 1
  No significant reduction in bacteriuria was observed with any of the three irrigants (saline, acetic acid, neomycin-polymyxin).
• 2
  A significant increase in urinary pH occurred in all three groups during the study.
• 3
  The occurrence of Enterococcus species increased significantly over time, especially in the neomycin-polymyxin group.