Factors Related to the Occurrence of Urinary Tract Infection Following a Urodynamic Study in Patients With Spinal Cord Injury

Neurogenic bladder, a common complication after spinal cord injury (SCI), can lead to recurrent urinary tract infections (UTIs) and kidney damage. Regular bladder function evaluation is crucial, with urodynamic studies (UDS) being a standard method. However, UDS carries a risk of UTI. The study aimed to identify risk factors for UTI following UDS in SCI patients, even with prophylactic antibiotics. Researchers retrospectively analyzed data from 140 SCI patients who underwent UDS with antibiotic prophylaxis. The study found that a history of UTI within the 4 weeks prior to UDS was a significant risk factor for developing a UTI post-UDS, despite the use of prophylactic antibiotics.

• 1
  A history of UTI within the past 4 weeks prior to the UDS was significantly associated with UTI occurrence after the UDS, even with prophylactic antibiotic therapy (p=0.006).
• 2
  Multivariable logistic regression analysis showed that the adjusted risk of UTI occurrence was 4.53 times higher in patients with a history of UTI within the past 4 weeks prior to the UDS (95% CI, 1.27–16.14).
• 3
  Previous autonomic dysreflexia showed a greater tendency to influence the UTI group, but this association was not statistically significant after multivariable analysis.