Idiopathic intracranial hypertension

J Neurol Neurosurg Psychiatry, 2001 · DOI: · Published: July 1, 2001

Simple Explanation

Obesity may contribute to increased intracranial pressure through hormonal mechanisms or direct pressure effects. Obesity-related increases in intra-abdominal, intrathoracic, and central venous pressures may directly cause increased intracranial pressure. IIH is likely a heterogeneous condition with various potential causes, including obesity as a risk factor or sufficient cause in some cases.

Study Duration

Not specified

Participants

Not specified

Evidence Level

Not specified

Key Findings

1
Obesity is likely only one of several risk factors for IIH, as obesity is common while IIH is rare and affects genders differently.
2
Weight reduction can effectively reduce intracranial pressure and resolve IIH symptoms.
3
IIH can occur without papilloedema, although response to medication may be poor in such cases.

Research Summary

Obesity is linked to increased intracranial pressure through mechanisms such as raised intra-abdominal and intrathoracic pressures. IIH is a heterogeneous condition, with obesity being a potential risk factor or sufficient cause in some individuals. Weight loss can effectively reduce intracranial pressure and resolve symptoms of IIH.

Practical Implications

Weight Management

Effective means of preventing or treating obesity would undoubtedly have an impact on the prevention and treatment of IIH.

Diagnostic Criteria

Consider IIH in obese patients with headache even without papilledema.

Further Research

Further study of cerebral and CSF volumes in IIH could provide more insight.

Study Limitations

1
The exact mechanisms by which obesity increases intracranial pressure are not fully understood.
2
The lack of a satisfactory concurrent control group in some studies limits the conclusions that can be drawn.
3
The heterogeneity of IIH makes it difficult to identify specific causes and treatments.

Your Feedback

Was this summary helpful?

Back to Endocrinology