Low-Level Laser Irradiation Improves Motor Recovery After Contusive Spinal Cord Injury in Rats

This research explores how low-level laser irradiation (LLLI) can aid recovery after spinal cord injury (SCI) in rats. The study focuses on whether LLLI can improve motor function and reduce inflammation following a spinal cord injury. The researchers used different doses of laser treatment on rats with spinal injuries. They monitored the rats' motor skills and checked for signs of inflammation in their spinal cords. The findings suggest that LLLI, especially at certain doses, can help rats regain motor function after spinal cord injury. This improvement is linked to reduced inflammation in the spinal cord.

• 1
  LLLI with 0.4 J and 0.8 J led to a significant improvement in motor function compared to sham LLLI.
• 2
  LLLI significantly decreased TNF-a expression at the lesion epicenter.
• 3
  LLLI reduced iNOS expression in the caudal segment for all LLLI groups and in the L4–5 segments for the 0.4 J and 0.8 J groups when compared to sham LLLI group.