Novel approach to an early assessment of a patient’s potential for neurological remission after acute spinal cord injury: Analysis of hemoglobin concentration dynamics

This study investigates the potential of using hemoglobin (Hb) levels as an early indicator of neurological recovery in patients with traumatic spinal cord injury (TSCI). The research team examined the relationship between Hb dynamics and neurological remission. The study found that elevated Hb concentrations in the early phase after TSCI (specifically 3 days post-injury) were associated with a higher likelihood of neurological remission. This suggests that Hb could be a valuable biomarker for predicting recovery potential. The findings suggest that maintaining adequate Hb levels in the acute phase after TSCI might support better tissue oxygenation and promote neural regeneration. This could inform future treatment strategies aimed at optimizing Hb levels to improve neurological outcomes.

• 1
  Elevated mean Hb concentrations were observed in the group with neurological remission (G1) from the third day to 1 month compared to the group without remission (G0).
• 2
  Hb levels were significantly higher in G1 after 3 days compared to G0 (P = 0.03).
• 3
  A multiple logistic regression model predicting neurological remission based on Hb data resulted in an AUC of 80.5% in the ROC analysis.