J Lasers Med Sci, 2022 · DOI: 10.34172/jlms.2022.28 · Published: June 23, 2022
Parkinson’s disease (PD) is a neurodegenerative disorder affecting the central nervous system, characterized by cell reduction in the substantia nigra and α-synuclein accumulation. Besides drug treatment, therapies like surgery, cell therapy, and laser therapy can be explored. This review evaluates the potential of cell therapy and laser therapy in PD for improving motor function, cell differentiation, and dopaminergic cell proliferation.
MSCs from various sources (umbilical cord, adipose tissue, bone marrow) can be used to improve motor function and neuronal survival in PD models.
PBM can be applied transcranially or intracranially to reduce inflammation, promote neuroprotection, and enhance motor skills in PD patients.
Combining cell therapy and photobiomodulation may offer synergistic benefits for treating PD symptoms.