Neural Regeneration Research, 2015 · DOI: 10.4103/1673-5374.162765 · Published: August 1, 2015
The study investigates whether propofol, a neuroprotective anesthetic, can enhance spinal cord injury repair when combined with bone marrow mesenchymal stem cell (BMSC) transplantation. Rats with spinal cord injuries were treated with either propofol, BMSC transplantation, a combination of both, or a control. The results showed that the combination therapy led to better spinal cord repair and improved motor function compared to individual treatments. The researchers suggest that propofol may increase the survival rate of BMSCs in the injured spinal cord, thus optimizing spinal cord injury repair.
The study suggests that combining propofol with BMSC transplantation can enhance spinal cord injury repair more effectively than using either treatment alone.
The findings suggest that this combined therapy could be a promising approach for treating spinal cord injuries in clinical settings.
The study provides insights into the potential mechanisms by which propofol may protect and promote neuronal regeneration in the injured spinal cord.