Case Reports in Neurological Medicine, 2022 · DOI: https://doi.org/10.1155/2022/9496652 · Published: July 6, 2022
This case report discusses a patient with a complete spinal cord injury who received olfactory ensheathing cell (OEC) transplantation. The patient experienced improvements in motor function, sensation, and activities of daily living after the transplantation. Specifically, the patient regained the ability to control urination and recovered normal sexual function after the OEC transplantation and subsequent neurorehabilitation. He was able to marry and father a child through natural sexual intercourse. The positive outcomes observed in this case highlight the potential of OEC transplantation as a neurorestorative therapy for individuals with chronic complete spinal cord injuries, although further research is needed to understand why some patients benefit more than others.
OEC transplantation may be a viable therapeutic option for patients with chronic complete SCI, particularly for recovering voiding and sexual function.
Intensive neurorehabilitation alongside OEC transplantation appears crucial for maximizing functional recovery in SCI patients.
Further research is needed to identify factors that predict which patients are most likely to benefit from OEC transplantation.