International Journal of Surgery, 2024 · DOI: http://dx.doi.org/10.1097/JS9.0000000000002109 · Published: November 5, 2024
Stem-cell therapy is a cutting-edge field in medicine that uses stem cells' unique abilities to regenerate and differentiate into various cell types to treat illnesses and injuries. Stem cells can repair damaged tissues, offering potential treatments for cancer, neurodegenerative disorders, cardiovascular ailments, spinal cord injuries, diabetes, and tissue damage. However, challenges like immune rejection and tumor formation need innovative solutions. Advances in biotechnology, such as exosome-based therapeutics and CRISPR technology, have revolutionized stem cell research, offering precise genome editing and therapeutic interventions. The future of stem cell therapy involves integrating precision medicine, immune modulation, gene editing, and bioengineering to create personalized regenerative therapies.
Tailoring healthcare based on individual characteristics, including genetic, environmental, and lifestyle factors, for enhanced therapeutic outcomes and reduced side effects.
Addressing challenges such as immune rejection and graft-versus-host responses through innovative approaches, including engineered stem cells and immunomodulatory molecules, to enhance compatibility with stem-cell treatment.
Integrating stem cells with advanced biomaterials to create functional tissues and organs with improved structural and functional properties for tissue-specific regeneration and transplantation.