Sacral neuromodulation for neurological disease-induced lower urinary tract symptoms in Saudi Arabia: a single-centre experience

Journal of International Medical Research, 2022 · DOI: 10.1177/03000605221117221 · Published: August 1, 2022

Simple Explanation

This study evaluates sacral neuromodulation (SNM) therapy for lower urinary tract symptoms (LUTS) caused by neurological diseases in Saudi Arabia. The study involved a two-stage procedure: a test phase (stage 1) to identify the best nerve response, followed by implantation of a permanent device (stage 2) if the patient showed significant improvement. The results showed that SNM significantly improved urinary symptoms and patient satisfaction was high, suggesting it's an effective treatment option for nLUTS.

Study Duration

March 2017 and August 2020

Participants

21 patients with neurological disorders

Evidence Level

Prospective cohort study

Key Findings

1
SNM significantly increased voided volume per void per day compared to baseline (P = 0.0001).
2
SNM significantly decreased leaking episodes per day (P = 0.001) and post-voiding residual per day (P = 0.002) compared to baseline.
3
A high rate of patient satisfaction was reported, with five patients highly satisfied and nine moderately satisfied with the therapy.

Research Summary

This prospective cohort study evaluated the effectiveness of sacral neuromodulation (SNM) for lower urinary tract symptoms (LUTS) caused by neurological diseases in a single center in Saudi Arabia. The study included 21 patients with various neurological etiologies, and those who responded positively to the first stage of SNM underwent full device implantation. The results indicated that SNM led to significant improvements in voiding volume, reduced leaking episodes, decreased post-voiding residual, and a high level of patient satisfaction.

Practical Implications

Clinical Practice

SNM can be considered as an effective therapy for managing LUTS caused by neurological diseases, particularly in patients who have not responded well to conservative and medical treatments.

Patient Selection

Careful patient selection is crucial, as the success rate varies based on the underlying neurological condition and the presence of detrusor-sphincter dyssynergia (DSD).

Further Research

Larger, multi-center studies are needed to validate these findings and explore the long-term efficacy and safety of SNM for nLUTS in diverse populations.

Sacral neuromodulation for neurological disease-induced lower urinary tract symptoms in Saudi Arabia: a single-centre experience

Simple Explanation

Key Findings

Research Summary

Practical Implications

Clinical Practice

Patient Selection

Further Research

Study Limitations

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Was this summary helpful?

Sacral neuromodulation for neurological disease-induced lower urinary tract symptoms in Saudi Arabia: a single-centre experience

Simple Explanation

Key Findings

Research Summary

Practical Implications

Clinical Practice

Patient Selection

Further Research

Study Limitations

Your Feedback

Was this summary helpful?