The Role of Vitamins in Spinal Cord Injury: Mechanisms and Benefits

Spinal cord injury (SCI) can result from trauma or spinal cord disease, leading to a wide range of neurological disorders and, in severe cases, even death. Vitamins are naturally occurring substances that play a crucial role in maintaining optimal human body functions. Since the body cannot synthesize these essential nutrients, they must be obtained from the diet. In this review, we summarize the underlying pathophysiological mechanisms of SCI and discuss the therapeutic potential of vitamins in its treatment.

• 1
  RA plays a vital role in neural differentiation processes in various types of stem cells, enhancing their effectiveness when combined with growth factors
• 2
  Folic acid (also known as folate, pteroylglutamic acid, or vitamin B9) is an essential water-soluble B vitamin that significantly enhances neuronal function and contributes to maintaining microenvironmental homeostasis in mice with SCI neurons, particularly when combined with mature neural stem cells
• 3
  Vitamin E is a fat-soluble vitamin with eight different forms, with alpha-tocopherol being the most biologically active. It serves as a potent antioxidant in the body, protecting cells from oxidative damage caused by free radicals.