Transcription Profiling of a Revealed the Potential Molecular Mechanism of Governor Vessel Electroacupuncture for Spinal Cord Injury in Rats

This study uses RNA sequencing (RNA-seq) to identify how governor vessel electroacupuncture (GV-EA) might help with spinal cord injury (SCI) recovery in rats. The study looks at gene expression changes after GV-EA treatment to understand potential molecular mechanisms involved in nerve survival and regeneration. The findings suggest that GV-EA can alter gene expression related to inflammation and nerve protection, offering insights for future SCI treatments.

• 1
  GV-EA treatment regulated the expression of 173 mRNA, 260 lncRNA, and 153 circRNA genes altered by SCI.
• 2
  GO enrichment analysis showed DEGs were most enriched in membrane, actin binding, and regulation of Toll-like receptor signaling pathway.
• 3
  KEGG pathway analysis showed enriched pathways like Toll-like receptors, MAPK, and Hippo signaling pathways.