Transspinal stimulation and step training alter function of spinal networks in complete spinal cord injury

This study investigates how combining transspinal stimulation with robot-assisted step training affects spinal cord function in individuals with complete spinal cord injury. The researchers looked at changes in reflex responses and motor output after the intervention. The study found that the combined intervention depressed the long-latency tibialis anterior (TA) flexion reflex, which is a specific reflex in the leg. At the same time, it increased the motor output of nerves controlling muscles in both the legs. These findings suggest that transspinal stimulation can enhance the benefits of locomotor training by promoting neuroplasticity, which is the ability of the nervous system to reorganize itself.

• 1
  The long-latency TA flexion reflex was depressed in all phases of the step cycle after the combined intervention.
• 2
  The phase-dependent amplitude modulation of transspinal evoked potentials (TEPs) was altered during assisted stepping following the intervention.
• 3
  Spinal motor output, as measured by TEP recruitment curves, was increased after the combined intervention.