Utilizing a low-carbohydrate/high-protein diet to improve metabolic health in individuals with spinal cord injury (DISH): study protocol for a randomized controlled trial
Trials, 2019 · DOI: https://doi.org/10.1186/s13063-019-3520-3 · Published: September 5, 2019
Simple Explanation
This study explores how a low-carbohydrate, high-protein diet might improve metabolic health in people with spinal cord injuries. Metabolic disorders are more common in this population. The study will involve 100 participants with SCI who will be randomly assigned to either follow an 8-week low-carbohydrate, high-protein diet or continue with their regular diet. The researchers will then examine the effects on glucose control, body composition, gut bacteria, and quality of life. The goal is to find a cost-effective dietary intervention that can improve metabolic function and overall health in individuals with chronic SCI.
Key Findings
- 1The study aims to determine if a low-carbohydrate/high-protein diet improves glucose tolerance, insulin sensitivity, and β-cell function in individuals with SCI.
- 2Researchers will assess changes in body composition, specifically increases in lean mass and decreases in total and visceral fat mass.
- 3The study will also examine how the dietary intervention affects the composition of gut bacteria and the overall quality of life for participants.
Research Summary
Practical Implications
Development of Dietary Intervention
The project aims to develop a low-cost, simple, self-administered LC/HP dietary intervention for improving metabolic function in individuals with chronic SCI.
Improved Understanding of Gut Bacteria
The study seeks to improve understanding of the composition of gut bacteria in SCI and how a LC/HP dietary intervention alters gut bacteria composition.
Enhanced Quality of Life
The project will improve understanding of the relationship between metabolic function and quality of life in individuals with long-standing SCI.
Study Limitations
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