Neurology Research

KEY FINDING: Around 6-8 weeks post-injury, the monkeys began to perform tasks, showing elevated activation of most motor pools beyond pre-lesion levels.

KEY FINDING: SCI and NT3 treatment both lead to an increase in the number of modules within the brain network, indicating enhanced functional separation.

KEY FINDING: Errors were identified in Figure 3 of the original article.

KEY FINDING: After SCI, the ratio of excitatory to inhibitory interneurons increases, indicating a reorganization of the spinal CPG neural circuit with more pronounced excitatory interneurons than inhibitory interneurons.

KEY FINDING: The primary outcome is neurological recovery at 10 weeks, measured with the Total Motor Score from the International Standards for Neurological Classification of SCI.

KEY FINDING: Boldine administration after SCI resulted in increased locomotor function compared to vehicle-treated animals, as assessed by the Basso Mouse Scale (BMS) and ladder rung walk test (LRWT).

KEY FINDING: A statistically significant linear trend was found between pulse charge and isometric torque production in both groups, with higher pulse charge resulting in higher torque.

KEY FINDING: Electron microscopy revealed direct physical damage, damaged myelin sheaths, and vacuolated axons in the spinal cord one day after electrical injury.

KEY FINDING: Early peri-operative neurological improvement occurred in 18 of the 142 study participants (12.7%) while AIS grade deterioration occurred in 6 individuals.

KEY FINDING: The participant with SCI showed improvements in blood pressure and gastric electrical activity after AFTE training.