AN ELECTRON MICROSCOPE STUDY OF THE ENDOPLASMIC RETICULUM IN NEWT NOTOCHORD CELLS AFTER DISTURBANCE WITH ULTRASONIC TREATMENT AND SUBSEQUENT REGENERATION

The Journal of Cell Biology, 1964 · DOI: · Published: January 1, 1964

Simple Explanation

The study investigates the effects of ultrasonic treatment on the endoplasmic reticulum (ER) in newt notochord cells using electron microscopy. Ultrasonic treatment disrupted the ER, causing it to form irregularly rounded vesicles instead of its normal parallel arrangement. Within 24 hours after treatment, the ER in the notochord cells showed a trend towards normality, with some re-ordering and new formation occurring near the nuclear surface.

Study Duration

Not specified

Participants

Triturus alpestris tadpoles between stages 34 and 41

Evidence Level

Level not specified, Electron Microscopy Study

Key Findings

1
Ultrasonic treatment disordered the endoplasmic reticulum (ER) in newt notochord cells into irregularly rounded vesicles.
2
Some parallel arrays of normal endoplasmic reticulum were observed near, and continuous with, the outer nuclear membrane within 3 hours after treatment.
3
A re-ordering of the previously disordered ER took place throughout the cytoplasm, and more than half of the ER was normal again by 24 hours after treatment.

Research Summary

This study examines the effects of ultrasonic treatment on the endoplasmic reticulum (ER) of newt notochord cells using electron microscopy. Ultrasonic treatment disrupted the ER into irregular vesicles, but the cells showed signs of recovery and re-ordering of the ER within 24 hours. The study suggests that the disruptive effects are primarily mechanical, and the cells have a capacity for repair and re-establishment of normal ER structure.

Practical Implications

Understanding Cellular Response

The study provides insights into how cells respond to physical stress at the ultrastructural level.

Implications for Therapeutic Ultrasound

The findings have implications for understanding the effects of therapeutic ultrasound on tissues.

Cellular Repair Mechanisms

The research highlights the capacity of cells to repair and reorganize their internal structures after damage.

AN ELECTRON MICROSCOPE STUDY OF THE ENDOPLASMIC RETICULUM IN NEWT NOTOCHORD CELLS AFTER DISTURBANCE WITH ULTRASONIC TREATMENT AND SUBSEQUENT REGENERATION

Simple Explanation

Key Findings

Research Summary

Practical Implications

Understanding Cellular Response

Implications for Therapeutic Ultrasound

Cellular Repair Mechanisms

Study Limitations

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AN ELECTRON MICROSCOPE STUDY OF THE ENDOPLASMIC RETICULUM IN NEWT NOTOCHORD CELLS AFTER DISTURBANCE WITH ULTRASONIC TREATMENT AND SUBSEQUENT REGENERATION

Simple Explanation

Key Findings

Research Summary

Practical Implications

Understanding Cellular Response

Implications for Therapeutic Ultrasound

Cellular Repair Mechanisms

Study Limitations

Your Feedback

Was this summary helpful?