Association Between Serum 25(OH)D Level and Nonspecific Musculoskeletal Pain in Acute Rehabilitation Unit Patients

JPEN J Parenter Enteral Nutr., 2016 · DOI: 10.1177/0148607114555909 · Published: March 1, 2016

Pain Management Nutrition & Dietetics Rehabilitation

Simple Explanation

This study explores the link between vitamin D levels and unexplained muscle and bone pain in patients in acute rehabilitation units (ARUs). These patients often experience such pain, which can be hard to treat. The researchers found that lower vitamin D levels were associated with a higher likelihood of having this type of pain. This suggests that vitamin D might play a role in managing musculoskeletal pain. The findings indicate a need for further research to see if giving vitamin D supplements can help reduce this pain in ARU patients. This could lead to new ways to improve their comfort and recovery.

Study Duration

1 Year

Participants

414 adults from an inpatient ARU

Evidence Level

Cross-sectional study

Key Findings

1
Serum 25(OH)D level was inversely associated with nonspecific musculoskeletal pain.
2
Patients with levels <20 ng/mL had higher odds of nonspecific musculoskeletal pain compared with patients with levels ≥20 ng/mL.
3
An inverse association between admission serum 25(OH)D levels and nonspecific musculoskeletal pain was demonstrated.

Research Summary

The study investigated the association between vitamin D status and nonspecific musculoskeletal pain in acute rehabilitation unit (ARU) patients. The results showed an inverse relationship between serum 25(OH)D levels and the presence of nonspecific musculoskeletal pain, suggesting that lower vitamin D levels are associated with higher odds of pain. The authors conclude that these findings support the need for randomized controlled trials to examine the potential of vitamin D supplementation in improving nonspecific musculoskeletal pain in ARU patients.

Practical Implications

Further Research

Randomized, controlled trials are needed to determine if vitamin D supplementation can effectively improve nonspecific musculoskeletal pain in ARU patients.

Potential Therapeutic Intervention

Vitamin D supplementation may be a potential strategy to manage nonspecific musculoskeletal pain in ARU patients, especially those with low vitamin D levels.

Clinical Screening

Screening ARU patients for vitamin D deficiency may help identify individuals at higher risk for nonspecific musculoskeletal pain, allowing for targeted interventions.

Study Limitations

1
Observational nature of the study limits causal inferences.
2
Potential residual confounding despite adjusting for multiple covariates.
3
Generalizability may be limited as patients were selected from a single institution.

Your Feedback

Was this summary helpful?

Back to Pain Management