DISTRIBUTION OF LEUCINE- 3H DURING AXOPLASMIC TRANSPORT WITHIN REGENERATING NEURONS AS DETERMINED BY ELECTRON-MICROSCOPE RADIOAUTOGRAPHY

This study uses radioactive labeling and electron microscopy to track how proteins move within nerve cells, specifically during limb regeneration in newts. The study looks at where the labeled proteins are found inside different parts of the nerve cells, like the main body, the long extensions (axons), and the nerve endings. The research aims to understand how proteins are transported within nerve cells as they rebuild and regenerate after injury.

• 1
  The highest concentration of labeled proteins was found in the rough endoplasmic reticulum of nerve cell bodies, which is where proteins are made.
• 2
  In axons, labeled materials are not evenly distributed, but are concentrated in a band near the edge of the axon, rich in microtubules.
• 3
  In nerve terminals, labeled material concentrates in a thin zone just beneath the plasma membrane.