Effect of aerobic exercise program on neuropathic pain and quality of life in person with paraplegia: study protocol for a randomized controlled trial

Trials, 2024 · DOI: https://doi.org/10.1186/s13063-024-08430-0 · Published: January 1, 2024

Spinal Cord Injury Pain Management Rehabilitation

Simple Explanation

This study investigates whether aerobic exercise can reduce neuropathic pain and improve quality of life in individuals with paraplegia. The study will involve two groups: one performing high-intensity interval training (HIIT) and the other performing free-hand arm aerobic exercise. The effectiveness of the exercise program will be assessed by measuring changes in pain scores, mood, sleep quality, overall quality of life, and aerobic capacity.

Study Duration

6 Weeks

Participants

30 individuals with chronic paraplegia

Evidence Level

Level 1, Randomized Controlled Trial

Key Findings

1
The trial aims to provide new knowledge about the effectiveness of aerobic exercise in improving neuropathic pain and QoL in individuals with chronic paraplegia.
2
The study will investigate if the intensity of aerobic exercise matters for its potential benefits.
3
It is hypothesized that HIIT will lead to a significant reduction in neuropathic pain and improved QoL compared to low-intensity exercise.

Research Summary

This study is a double-blind, randomized controlled trial designed to assess the impact of aerobic exercise on neuropathic pain and quality of life in individuals with chronic paraplegia. Participants will be divided into two groups: one receiving high-intensity interval training (HIIT) using an arm ergometer, and the other performing free-hand arm aerobic exercise. The primary outcome measures include neuropathic pain score, QoL, and aerobic capacity, which will be assessed at baseline, mid-intervention (3 weeks), and post-intervention (6 weeks).

Practical Implications

Clinical Practice

The results may support the incorporation of aerobic exercise into multidisciplinary rehabilitation programs for individuals with SCI to manage neuropathic pain.

Economic Impact

Demonstrating the effectiveness of aerobic exercise could reduce reliance on pharmacological treatments, potentially decreasing the economic burden of neuropathic pain.

Future Research

The study can inform future research exploring the physiological mechanisms underlying the analgesic effects of aerobic exercise in the SCI population.

Study Limitations

1
The therapist administering the treatment will not be blinded.
2
Recruitment of participants will be done through a convenience sample which may result in a possible selection bias.
3
Not specified

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