Effect of imidafenacin on the urodynamic parameters of patients with indwelling bladder catheters due to spinal cord injury

This study investigates the effects of imidafenacin, a medication, on bladder function in patients with spinal cord injury (SCI) who use indwelling bladder catheters. The researchers aimed to see if imidafenacin could improve bladder capacity and compliance, and reduce bladder pressure in these patients. The study found that imidafenacin may improve bladder parameters and reduce complications in SCI patients with indwelling catheters.

• 1
  Imidafenacin increased the cystometric volume from 246.0 to 321.5 ml (median, P = 0.002).
• 2
  Detrusor compliance increased from 6.67 ml cm−1 H2O to 8.98 ml cm −1 H2O (median, P = 0.012).
• 3
  All three patients who had VUR fully recovered with imidafenacin treatment.