Neural Regeneration Research, 2015 · DOI: 10.4103/1673-5374.158361 · Published: June 1, 2015
This study investigates the potential of hydrogen-rich saline to aid in the repair of spinal cord injuries in rats. The hypothesis is that hydrogen-rich saline can reduce the damage caused by spinal cord injury. The rats received injections of hydrogen-rich saline into the subarachnoid space, and the researchers monitored cell death, inflammation, and motor function. They found that hydrogen-rich saline reduced cell death and improved motor function. The results suggest that hydrogen-rich saline can effectively contribute to the repair of spinal cord injury in the acute stage. This indicates the potential for hydrogen-rich saline as a therapeutic intervention for spinal cord injuries.
Hydrogen-rich saline shows promise as a potential treatment for spinal cord injuries due to its ability to reduce cell death and inflammation, and improve motor function.
The study provides insights into the mechanism of action of hydrogen-rich saline, involving the antioxidant system, CGRP, and caspase-3, which could guide further research and development of targeted therapies.
The findings support further investigation into the clinical application of hydrogen-rich saline for the treatment of SCI and other conditions associated with oxidative damage, inflammation, and apoptosis.