Relationship Between Gonadal Function and Cardiometabolic Risk in Young Men with Chronic Spinal Cord Injury

This study investigates the link between testosterone levels and heart health risks in young men with long-term spinal cord injuries (SCI). Men with SCI often face a higher risk of heart and metabolic problems. The research found that lower testosterone levels are associated with increased body fat, lower good cholesterol (HDL), higher fasting glucose, and greater insulin resistance in these men. These findings suggest that monitoring testosterone levels in men with SCI could help identify those at higher risk for heart and metabolic diseases, allowing for earlier intervention and preventative strategies.

• 1
  Men with low free testosterone had significantly higher Framingham Risk Scores, indicating a greater risk of cardiovascular events.
• 2
  Lower total and free testosterone levels were associated with higher body fat percentages and lower HDL cholesterol levels.
• 3
  Men with low total or free testosterone exhibited higher fasting glucose levels and greater insulin resistance, suggesting impaired glucose metabolism.