Research progress on the role of ginsenoside Rd in central nervous system diseases

Ginsenoside Rd (GSRd) is a rare saponin from ginseng with potential for treating neurological diseases because it can cross the blood-brain barrier. Research suggests GSRd can help with conditions like ischemic stroke, spinal cord injury, Alzheimer's, and Parkinson's disease by protecting nerve cells and reducing inflammation. Clinical trials for ischemic stroke show that GSRd can improve patient outcomes without significant adverse effects, making it a promising drug candidate.

• 1
  Ginsenoside Rd (GSRd) has shown protective effects in neurological diseases such as ischemic stroke, spinal cord injury, Alzheimer's disease and Parkinson's disease.
• 2
  In ischemic stroke, GSRd can improve cerebral infarction, neurological outcomes, and increase the survival rate of rats and the recovery of nerve function.
• 3
  In Alzheimer's disease, GSRd can improve learning and memory ability, possibly by inhibiting the transcriptional activity of NF-κB.