The Journal of Spinal Cord Medicine, 2014 · DOI: 10.1179/2045772313Y.0000000172 · Published: January 1, 2014
This study investigates if a non-invasive brain stimulation technique, repetitive transcranial magnetic stimulation (rTMS), can reduce chronic nerve pain in patients with spinal cord injuries (SCI). rTMS uses magnetic pulses to alter brain activity. The study compared real rTMS to a sham treatment. Patients received ten daily sessions of either real or sham rTMS, and their pain levels were assessed at baseline, 10 days, 6 weeks, and 6 months after treatment. The results showed both real and sham rTMS reduced pain. However, the pain relief wasn't significantly different between the two groups, suggesting the benefit might be due to a placebo effect. The researchers suggest further studies with more patients.
rTMS may not provide a significant advantage over placebo for treating neuropathic pain in SCI patients in a clinical setting.
Larger studies are warranted to investigate the potential of rTMS for mid-term pain relief in SCI patients with neuropathic pain.
Future studies should consider using more reliable and valid sham controls, such as recently developed sham coils, to account for sensory aspects of stimulation.