Browse the latest research summaries in the field of neuroimaging for spinal cord injury patients and caregivers.
Showing 81-90 of 90 results
BRAIN, 2016 • April 21, 2016
Embodied neurology is a framework that emphasizes the importance of reciprocal interactions between the nervous system and the body in understanding and treating neurological disorders. The approach i...
KEY FINDING: Reciprocal information flows between the body and the nervous system are crucial for understanding and treating neurological disorders.
Neuroimage, 2009 • May 1, 2009
This study investigated the use of quantitative MRI techniques (qT2 and MTR) to assess demyelination and remyelination in a mouse model of multiple sclerosis. Lysolecithin was injected into the spinal...
KEY FINDING: The myelin water fraction (MWF) and geometric mean T2 value significantly decreased at 14 days post-injection, indicating demyelination. By 28 days, these values returned to control levels, suggesting remyelination.
PLoS ONE, 2016 • August 25, 2016
This study compares three different dMRI protocols applied to investigate the microstructure of both gray (GM) and white matter (WM) in the lumbar region of the mouse spinal cord. The protocols were c...
KEY FINDING: Intermediate features (12 directions, b = 1200 s/mm2) provided the overall minimum inter- and intra-subject variability in most cases.
World Neurosurg, 2014 • December 1, 2014
Advanced spinal cord imaging has great potential to offer specific physiological details regarding cord integrity and health. Though advanced spinal cord imaging is still in early development and impl...
KEY FINDING: Conventional MRI may not consistently correlate with clinical findings post-SCI, prompting interest in microstructural and metabolic imaging.
Journal of Medical Case Reports, 2022 • November 30, 2022
This case report describes an 81-year-old man who developed unilateral delayed post-hypoxic leukoencephalopathy (DPHL) following a dissection-related occlusion of the left carotid artery. The patient ...
KEY FINDING: Clinical symptoms suggestive of delayed post-hypoxic leukoencephalopathy (DPHL) can be observed in very rare cases following successful revascularization therapy in large vessel occlusions, causing acute ischemic stroke.
J Neurol Neurosurg Psychiatry, 2012 • June 1, 2012
This study investigates the relationship between axonal integrity in the corticospinal tract (CST), spinal cord area, and cortical reorganization in subjects with traumatic spinal cord injury (SCI) us...
KEY FINDING: Diffusion tensor imaging showed significant differences in the CST of SCI subjects compared to controls in areas such as the pyramids, internal capsule, cerebral peduncle, and hand area.
Frontiers in Neurology, 2019 • March 26, 2019
This study demonstrates the feasibility of using functional ultrasound (fUS) imaging to monitor spinal cord hemodynamic responses to epidural electrical stimulation (SCS) in animal models. The researc...
KEY FINDING: fUS can detect spinal cord hemodynamic responses to epidural electrical stimulation (SCS) in both rat and swine models.
Neurology, 2019 • March 12, 2019
This study summarizes current and emerging imaging techniques for assessing neuroprotection and repair in multiple sclerosis (MS). It provides a consensus opinion on each technique's utility in clinic...
KEY FINDING: Conventional MRI measures in acute lesions can assess myelin integrity and repair, leveraging routinely collected data, though lacking pathologic specificity and requiring signal normalization.
The Neuroradiology Journal, 2013 • January 1, 2013
Extramedullary hematopoiesis (EMH) can occur in patients with thalassemia intermedia as a physiologic response to insufficient erythropoiesis to meet circulatory demands. Magnetic resonance imaging (M...
KEY FINDING: MRI demonstrated spinal cord compression by EMH epidural mass lesions extending from T3 to T10 levels.
Neurobiology of Aging, 2014 • February 15, 2014
The study uses quantitative multiparameter mapping (MPM) to identify widespread age-related differences in the microstructure of the human brain. MPM quantifies R1, R2*, MT, and PD*. Significant demye...
KEY FINDING: Significant demyelination occurs primarily in the white matter, with anatomically specific age-related differences in myelination observed.