Browse the latest research summaries in the field of neurology for spinal cord injury patients and caregivers.
Showing 61-70 of 5,253 results
Spinal Cord Series and Cases, 2023 • April 3, 2023
This study investigated the impact of COVID-19 restrictions on spasticity management in individuals with spinal cord injury (SCI). The results showed a significant increase in spasticity among partici...
KEY FINDING: 75% of participants reported a moderate increase in spasticity during the COVID-19 pandemic restrictions.
Frontiers in Neurology, 2023 • April 6, 2023
This study evaluated the clinical efficacy of BoNT-A in reducing spasticity, pain, and improving QoL in patients with SCI, TBI, and MS. The study design was an observational, multicentre, non-interven...
KEY FINDING: BoNT-A significantly reduces spasticity and pain, and improves QoL in patients with MS, SCI, and TBI up to 3 months after injection.
J. Clin. Med., 2023 • April 16, 2023
This case series investigated the real-time effect of epidural spinal cord stimulation (eSCS) on mitigating autonomic dysreflexia (AD) in individuals with spinal cord injury (SCI). The study demonstra...
KEY FINDING: Epidural spinal cord stimulation (eSCS) can reduce the elevation in blood pressure and prevent digital anorectal stimulation (DARS)-induced autonomic dysreflexia (AD) in individuals with spinal cord injury (SCI).
Frontiers in Neurology, 2023 • April 11, 2023
This case report details the successful implementation of continuous intraspinal pressure monitoring using a strain gauge pressure monitor in a patient with acute traumatic spinal cord injury. The pro...
KEY FINDING: Intraspinal pressure can be measured safely and effectively at the site of injury using a subdural strain gauge pressure monitor.
Life Sci., 2023 • July 15, 2023
This study investigated the role of p38 MAPK in the hyperexcitability of capsaicin-sensitive bladder afferent neurons in mice with spinal cord injury (SCI). The findings suggest that p38 MAPK plays an...
KEY FINDING: SCI significantly reduced the spike threshold and increased the number of action potentials during 800 ms membrane depolarization in capsaicin-sensitive bladder afferent neurons.
Proc Inst Mech Eng H, 2024 • June 1, 2024
This study tested the feasibility of automated closed-loop genital nerve stimulation (GNS) using a custom algorithm to identify and inhibit reflex bladder contractions in real time in individuals with...
KEY FINDING: The custom algorithm detected bladder contractions in real time, successfully inhibiting a total of 56 contractions across all four subjects.
Spinal Cord Series and Cases, 2023 • April 25, 2023
This case report describes a 63-year-old male with incomplete paraplegia who developed restless leg syndrome (RLS) four years after his spinal cord injury (SCI). The patient was successfully treated w...
KEY FINDING: A 63-year-old man with incomplete paraplegia developed RLS four years post spinal cord injury.
Journal of NeuroEngineering and Rehabilitation, 2023 • May 16, 2023
This study investigates the impact of epidural spinal cord stimulation (eSCS) on neuromuscular control in individuals with motor and sensory complete spinal cord injury (SCI). It analyzes changes in m...
KEY FINDING: Epidural stimulation immediately reduces the complexity of muscle activity in SCI participants, bringing it closer to the complexity levels seen in healthy controls.
Frontiers in Neuroscience, 2023 • April 17, 2023
This paper introduces a sequential learning model incorporating a Graph Isomorphic Network (GIN) that processes a sequence of graph-structured data derived from EEG and EMG signals for stroke rehabili...
KEY FINDING: The proposed GIN-based model achieved a classification accuracy of 88.89% on an EEG-EMG synchronized dataset for push and pull movements.
Scientific Reports, 2023 • May 1, 2023
This study examined metabolic profiles in the pons and cerebellum of individuals with complete SCI using magnetic resonance spectroscopy, revealing differences in tNAA, GSH, and choline levels compare...
KEY FINDING: Lower total N-acetyl-aspartate (tNAA) was found in the pons of chronic SCI participants compared to healthy controls.