Browse the latest research summaries in the field of neuroplasticity for spinal cord injury patients and caregivers.
Showing 81-90 of 159 results
IEEE Trans Neural Syst Rehabil Eng, 2018 • June 1, 2018
This study investigated the effects of transcutaneous electrical spinal cord stimulation combined with physical therapy on upper extremity function in a 62-year-old male with chronic tetraplegia. The ...
KEY FINDING: Upper extremity muscle strength nearly doubled over the course of treatment and stabilized at 75% stronger than baseline for three months without further treatment.
Neurotherapeutics, 2018 • June 26, 2018
This review addresses the potential for activating residual corticospinal projections after SCI to improve motor recovery. It discusses evidence showing that spinal cord injuries are rarely anatomical...
KEY FINDING: A large proportion of individuals with clinically complete SCI show signs of spared connections, categorized as 'discomplete'.
Neurotherapeutics, 2018 • June 11, 2018
Recent advances in neuroscience and devices are ushering in a new generation of medical treatments, with engineered biodevices demonstrating the potential to create long-term changes in neural circuit...
KEY FINDING: Neural devices operating in a closed-loop, activity-dependent paradigm can powerfully influence neural circuits, leading to long-term rewiring of neural circuits that outlasts stimulation.
Trends Neurosci, 2018 • September 1, 2018
Spinal interneurons (SpINs) are essential for neuroplasticity after spinal cord injury, influencing motor and sensory functions. Advances in genetics and developmental neurobiology are enhancing the u...
KEY FINDING: SpINs are key cellular elements for plasticity following spinal cord injury.
Neural Regeneration Research, 2019 • March 1, 2019
Spinal cord injury is a devastating condition, and rehabilitation is the most effective strategy for managing paralysis and impairments. Rodent models of rehabilitation can help reveal the axonal chan...
KEY FINDING: Animal models of SCI rehabilitation, such as treadmill training and wheel running, can mimic clinical rehabilitation and reveal axonal changes underlying motor recovery.
Frontiers in Neurology, 2018 • December 11, 2018
The Arm Ability Training (AAT) is specifically designed for individuals with brain injuries causing mild to moderate arm weakness and reduced dexterity, addressing sensorimotor efficiency across vario...
KEY FINDING: AAT is clinically effective in promoting dexterity recovery and reducing focal disability in stroke patients with mild to moderate arm paresis.
Physiol Rep, 2019 • July 1, 2019
This study investigated the impact of HIIT on brain excitability, biochemical markers, and working memory in sedentary young males. Eighteen participants underwent 6 weeks of HIIT, and various measure...
KEY FINDING: HIIT significantly increased cardiorespiratory fitness (CRF) in sedentary males after 6 weeks.
Neural Plasticity, 2012 • April 10, 2012
Spinal cord injury (SCI) leads to changes in body homeostasis, affecting multiple systems. In most cases, the spinal cord isn't completely severed, leaving some nerve pathways intact. This allows the ...
KEY FINDING: BWSTT increases the MEP amplitude, changes the common drive of antagonist muscles from corticospinal inputs with subjects seated, and alters the TA MEP modulation pattern during BWS assisted stepping.
Frontiers in Physiology, 2012 • July 18, 2012
This study evaluates the effects of treadmill and cycle locomotor training on spasticity, reflex excitability, and limb use in rats with spinal cord injuries. The results indicate that both types of l...
KEY FINDING: Locomotor training, whether treadmill or bicycle, significantly reduces spasticity in rats with spinal cord injuries.
The Journal of Spinal Cord Medicine, 2014 • January 1, 2014
This study investigated the effects of functional electrical stimulation (FES) on locomotor recovery in rats with spinal cord injury (SCI). Rats were divided into FES therapy and sedentary control gro...
KEY FINDING: FES significantly improved locomotion recovery in SCI rats by day 7, as measured by BBB scores. The FES group had a significantly higher score compared to the control group.