Browse the latest research summaries in the field of orthopedics for spinal cord injury patients and caregivers.
Showing 11-20 of 352 results
Cureus, 2023 • April 26, 2023
White cord syndrome (WCS) is a rare complication following spinal decompressive surgery, leading to neurological deterioration due to ischemic reperfusion injury. Diagnosis of WCS relies on MRI findin...
KEY FINDING: The patient developed bilateral C8 numbness six days post-operation, which progressively worsened to right hemisensory loss and right triceps atrophy.
Frontiers in Medicine, 2023 • June 8, 2023
This study aimed to explore the molecular events related to bone defect progression using bioinformatic analysis of transcriptome data and experimental validation. Key findings include the identificat...
KEY FINDING: The study identified 2057, 827, and 1,024 DEGs at 7, 14, and 21 days post injury, respectively, in critical size defects (CSD) compared to non-critical size defects (NCSD).
Dtsch Arztebl Int, 2023 • July 21, 2023
Modern hand surgery techniques can restore upper limb function in selected tetraplegic patients. Muscle and tendon transfers, tenodeses, and joint stabilizations can reliably improve upper limb functi...
KEY FINDING: Tendon transfers improved elbow extension strength and grip strength.
Journal of Orthopaedic Case Reports, 2023 • June 1, 2023
This case report describes a patient who developed White Cord Syndrome (WCS) after anterior cervical corpectomy and fusion (ACCF). The patient presented with acute neurologic deterioration post-operat...
KEY FINDING: A 64-year-old female patient with a C5-C6 tubercular lesion experienced acute neurologic deterioration (ASIA A grade) after undergoing ACCF.
Global Spine Journal, 2025 • February 1, 2025
This retrospective multicenter study analyzed 140 elderly patients with cDISH-related injuries (106 fractures, 34 SCI without fracture) compared to matched controls. Patients with cDISH-related fractu...
KEY FINDING: Elderly patients with cDISH-related spine injuries involving fractures did not show significantly different complication rates, ambulation outcomes, or paralysis severity compared to matched controls.
eLife, 2023 • July 18, 2023
The study conducts a meta-analysis of genome-wide association studies (GWASs) using 22,016 Japanese individuals and identifies 14 significant loci, 8 of which were previously unreported. A Mendelian r...
KEY FINDING: Identified 14 significant loci associated with OPLL, including 8 previously unreported loci.
Cureus, 2023 • June 29, 2023
This case report describes a rare presentation of Postural Orthostatic Tachycardia Syndrome (POTS) in a young female patient with a traumatic spinal cord injury (SCI). The patient developed POTS durin...
KEY FINDING: The patient experienced a significant increase in heart rate (35-40 bpm) upon tilting, without a drop in blood pressure, leading to the diagnosis of POTS after excluding other potential causes of tachycardia and syncope.
Frontiers in Endocrinology, 2023 • July 26, 2023
The editorial discusses how bone homeostasis affects tumor bone metastasis, highlighting that bone metastasis is a common complication of malignant tumors, influenced by interactions in the bone micro...
KEY FINDING: Dysregulation of bone remodeling impairs immune cell function, leading to immune evasion and promoting tumor cell survival and growth in the bone.
BMC Musculoskeletal Disorders, 2024 • October 21, 2024
This retrospective study compared the efficacy of ROI-C and conventional cage-plate (CCP) in improving cervical stability in patients with spinal cord injury without fracture or dislocation (SCIWFD). ...
KEY FINDING: Both ROI-C and CCP groups achieved bony fusion at the final follow-up, indicating similar efficacy in promoting spinal stability.
BMC Musculoskeletal Disorders, 2023 • July 27, 2023
This case report presents a 38-year-old female patient with Klippel-Feil syndrome (KFS) who developed Brown-Sequard syndrome (BSS) after a minor traumatic episode. The patient underwent surgical treat...
KEY FINDING: A patient with Klippel-Feil syndrome (KFS) developed Brown-Sequard syndrome (BSS) following a minor trauma.