Rheumatology Research

Browse the latest research summaries in the field of rheumatology for spinal cord injury patients and caregivers.

Showing 1-10 of 16 results

Imaging Characterization of Non-Rheumatoid Retro-Odontoid Pseudotumors: Comparison with Atlantoaxial Manifestation of Rheumatoid Arthritis

Medicina, 2022September 19, 2022

The study aimed to differentiate NRROPs from RA based on imaging characteristics, as treatment strategies differ for each condition. The study found that NRROPs are characterized by significant retro-...

KEY FINDING: NRROPs showed more prominent retro-odontoid soft tissue thickening compared to RA.

Case report: Clinical highlights and radiological classification of IgG4-related spinal pachymeningitis: A rare case series and updated review of the literature

Frontiers in Oncology, 2023January 10, 2023

The study reports three cases of IgG4-RSP and reviews 45 cases total, highlighting the disease's clinical presentations, radiological manifestations, treatment, and prognosis. Key findings include the...

KEY FINDING: Progressive worsening of neurological impairment was observed in nearly half of the patients (48.9%).

Unusual Cause of Cord Compression in a Patient with Chronic Lymphocytic Leukemia

Am J Case Rep, 2023March 23, 2023

This case report describes an unusual presentation of spinal gout causing cord compression in a patient with chronic lymphocytic leukemia who had no prior diagnosis of gout or hyperuricemia. The patie...

KEY FINDING: The patient presented with rapid and progressive weakness of the lower extremities leading to complete paraplegia over 2 weeks.

C1‑C2 subluxation in enthesitis‑related arthritis: two case reports and literature review of ten cases

Pediatric Rheumatology, 2023July 24, 2023

C1-C2 subluxation refers to the partial displacement of C1 and C2 that limits the movement or rotation of the neck. Initial management of C1-C2 subluxation in ERA should be focused on protecting the c...

KEY FINDING: The diagnosis of C1-C2 subluxation is mostly based on radiographs and cervical spine computed tomography.

Acute spinal cord infarction secondary to ankylosing spondylitis: a case report and literature review

Frontiers in Neurology, 2023September 22, 2023

This case report presents a rare instance of acute spinal cord infarction (SCI) in a patient with ankylosing spondylitis (AS). The patient presented with sudden lower limb weakness and was diagnosed w...

KEY FINDING: A 54-year-old man with a history of ankylosing spondylitis, scoliosis, and hypotension presented with acute spinal cord infarction.

Intramedullary Spinal Hemorrhage in Behcet’s Syndrome: A Case Report and Systematic Review

Cureus, 2023October 16, 2023

This is a rare case of spontaneous intramedullary spinal cord hemorrhage in a patient with BS. The existing literature documenting cases of spontaneous hemorrhages in patients with BS reflects the imm...

KEY FINDING: The case presents the first reported instance of an abrupt onset of neurological injury secondary to intramedullary spinal cord bleed in Behcet’s syndrome.

Stem cell-based therapy for systemic sclerosis

Rheumatology Advances in Practice, 2023November 20, 2023

This review discusses the efficacy of stem cell therapy (SCT) using mesenchymal stem cells (MSCs) and hematopoietic stem cells (HSCs) for systemic sclerosis (SSc). Both MSCT and HSCT could improve dis...

KEY FINDING: Mesenchymal stem cells (MSCs) and hematopoietic stem cells (HSCs) improve disease activity and severity in SSc patients.

PLCG2 and IFNAR1: The Potential Biomarkers Mediated by Immune Infiltration and Osteoclast Differentiation of Ankylosing Spondylitis in the Peripheral Blood

Mediators of Inflammation, 2024January 5, 2024

The study aimed to identify key biomarkers related to immune infiltration and osteoclast differentiation in ankylosing spondylitis (AS) using bioinformatic methods on publicly available microarray dat...

KEY FINDING: 125 DEGs were identified, consisting of 36 upregulated and 89 downregulated genes that are involved in the cell cycle and replication processes.

Psychometric Properties of the Persian Version of the Evaluation of Ankylosing Spondylitis Quality of Life (EASi‐QoL) and Ankylosing Spondylitis Disease Activity Score (ASDAS) Questionnaires: A Cross‐Sectional Study

Health Science Reports, 2025January 10, 2025

The Persian versions of both the ASDAS and the EASi‐QoL questionnaires were found to be valid and reliable for use in patients with ankylosing spondylitis. The EASi-QoL questionnaire was validated for...

KEY FINDING: The Persian version of the EASi‐QoL questionnaire demonstrated adequate reliability and validity for assessing quality of life in Iranian AS patients.

Severe Transverse Myelitis Following Ankle Surgery Potentially Unmasking Late-Onset Systemic Lupus Erythematosus

Cureus, 2024November 19, 2024

This case report describes a 70-year-old female who developed severe transverse myelitis following ankle surgery. The transverse myelitis was potentially unmasking late-onset systemic lupus erythemato...

KEY FINDING: The patient presented with transverse myelitis symptoms after ankle surgery, which is an unusual presentation.