Relationship Between the Systemic Immune-Inflammation Index and Deep Venous Thrombosis After Spinal Cord Injury: A Cross-Sectional Study

This study investigated the link between the systemic immune-inflammation index (SII) and deep vein thrombosis (DVT) in patients with spinal cord injury (SCI). We found that 23.1% of SCI patients had DVT. The risk of DVT was significantly increased by 39% with each 1-point increase in SII (OR = 1.39, 95% CI: 1.03–1.87, p = 0.031). Our results showed that higher SII values were associated with an increased risk of DVT, independent of other factors. This suggests that SII may be used as a potential biomarker to predict DVT in SCI patients, highlighting the importance of early detection and intervention.

• 1
  A positive association between SII and the risk for DVT was observed (odds ratio 1.39 [95% CI 1.03–1.87]; P=0.032), independent of confounders.
• 2
  Similar patterns of association were observed in the subgroup analysis (P values for interaction, all >0.05).
• 3
  Results of the present suggest that higher SII may be associated with DVT in patients with SCI, highlighting a potential link between SII and DVT.