Cardiovascular Science Research
Browse the latest research summaries in the field of cardiovascular science for spinal cord injury patients and caregivers.
Showing 31-40 of 339 results
The evolution of arch surgery: Frozen elephant trunk or conventional elephant trunk?
Frontiers in Cardiovascular Medicine, 2022 • October 20, 2022
This meta-analysis compares the outcomes of conventional elephant trunk (ET) and frozen elephant trunk (FET) techniques for aortic arch surgery, focusing on early mortality and major complications. Th...
KEY FINDING: ET is associated with higher early mortality compared to FET (RR 1.37 [1.04 to 1.81], p = 0.027) when considering all studies published between 2008 and 2021.
Extramedullary hematopoiesis causing spinal cord compression in polycythemia vera: A case report and literature review
Clinical and Translational Radiation Oncology, 2023 • January 1, 2023
This case report describes a patient with polycythemia vera who developed spinal cord compression due to extramedullary hematopoiesis and was successfully treated with radiotherapy. Radiotherapy, usin...
KEY FINDING: Radiotherapy effectively treated spinal cord compression caused by extramedullary hematopoiesis in a patient with polycythemia vera.
The Importance of Vascular Repair as the First Step in Spinal Cord Injury Treatment: Commentary on “Therapeutic Approaches Targeting Vascular Repair After Experimental Spinal Cord Injury: A Systematic Review of the Literature”
Neurospine, 2022 • December 1, 2022
This commentary emphasizes the often-overlooked importance of vascular repair as a critical first step in spinal cord injury (SCI) treatment, enabling proper perfusion and treatment delivery. The revi...
KEY FINDING: Vascular repair is critical for proper perfusion pressure and the effective delivery of drugs or cells to the damaged spinal cord tissue.
Lower Body Perfusion Reduces the Morbidity of Postoperative Acute Kidney Injury in Type A Dissection: A Propensity-Matched Analysis
Braz J Cardiovasc Surg, 2023 • July 1, 2023
This study retrospectively analyzed 304 patients with acute type A aortic dissection who underwent total aortic arch replacement combined with frozen elephant trunk implantation between May 2016 and D...
KEY FINDING: LBP resulted as a safe and feasible approach in aortic arch surgery.
Surgical outcomes of spinal cavernous malformations: A retrospective study of 98 patients
Frontiers in Surgery, 2023 • January 12, 2023
This retrospective study analyzed the surgical outcomes of 98 patients with spinal cord cavernous malformations (SCCM) treated between 2009 and 2018. The study found that patients with dorsal or super...
KEY FINDING: Patients with dorsal or superficial lesions showed better improvement than those with ventral or lateral deep lesions.
Cav1.3-selective inhibitors of voltage-gated L-type Ca2+ channels: Fact or (still) fiction?
British Journal of Pharmacology, 2023 • May 1, 2023
This review assesses the existing evidence for Cav1.3-selective calcium channel blockers, which are of interest for treating various diseases. It finds that currently available compounds lack sufficie...
KEY FINDING: Current Cav1.3-selective blockers lack validation. The review finds no pharmacological tools suitable to confirm or refute a role of Cav1.3 channels in cellular responses due to selectivity issues.
Sex-Related Differences in Clinical Outcomes After Thoracic Endovascular Aortic Repair
J Am Heart Assoc, 2023 • January 1, 2023
This study from the Nationwide Readmissions Database (NRD) analyzed patients who underwent TEVAR from 2010 to 2018, finding that men were more likely to undergo TEVAR for type B aortic dissection, whi...
KEY FINDING: Women are more likely to undergo TEVAR for aneurysms, while men are more likely to undergo TEVAR for type B aortic dissection.
Remote ischemic preconditioning protects against spinal cord ischemia–reperfusion injury in mice by activating NMDAR/AMPK/PGC‑1α/SIRT3 signaling
Cell & Bioscience, 2023 • March 27, 2023
This study investigates the protective effects of remote ischemic preconditioning (RIPC) against spinal cord ischemia-reperfusion injury (SCIRI) in mice. The study identifies SIRT3 as a key protein me...
KEY FINDING: RIPC improves motor function and reduces neuronal loss after SCIRI in mice.
Outcomes Following Thoracic Endovascular Aortic Repair for Blunt Thoracic Aortic Injury Stratified by Society for Vascular Surgery Grade
J Vasc Surg, 2023 • July 1, 2023
Following TEVAR for BTAI, SVS aortic injury grade was not associated with perioperative and 5-year mortality. Over 5% of patients undergoing TEVAR belonged to grade 1, and these patients had high rate...
KEY FINDING: Following TEVAR for BTAI, grade 4 aortic injury patients experienced the highest rates of perioperative mortality, aortic-related mortality, and 5-year mortality.
Posterior Reversible Encephalopathy Syndrome After Thoraco-Abdominal Aortic Replacement
EJVES Vascular Forum, 2023 • January 1, 2023
The case report describes a 61-year-old man who developed paraplegia and blindness following thoraco-abdominal aortic aneurysm repair, later diagnosed as Posterior Reversible Encephalopathy Syndrome (...
KEY FINDING: Excessive induced hypertension for spinal cord protection could lead to cerebral vascular dysfunction, resulting in irreversible neurological damage.