Browse the latest research summaries in the field of dermatology for spinal cord injury patients and caregivers.
Showing 101-110 of 158 results
Molecular Pain, 2018 • June 8, 2018
This study investigates the therapeutic potential of Pak1 inhibition for pain associated with cutaneous burn injury using romidepsin, an FDA-approved inhibitor. The findings demonstrate that Pak1 inhi...
KEY FINDING: Inhibition of Pak1 by romidepsin decreased dendritic spine dysgenesis in the dorsal horn of mice with burn injury.
Eur J Transl Myol, 2018 • November 12, 2018
This study evaluates skin biopsies from SCI patients to determine if the Interdigitation Index, a measurement of the epidermal-dermal junction, can provide quantitative evidence of skin flattening. Th...
KEY FINDING: The Interdigitation Index of skin biopsies from SCI persons showed a significant linear correlation with the years from SCI (p < 0.001), indicating progressive skin flattening with longer SCI duration.
Trials, 2019 • January 8, 2019
This research project consists of an epidemiological analysis, called study 1, and a randomized controlled pilot trial (RCT), called study 2. In study 1, the aim is to analyze the epidemiology of pers...
KEY FINDING: Epidemiological knowledge of persons with SCI and PUs will provide insight of this complication
Medicine, 2019 • January 1, 2019
The study demonstrates the methods of controlling contributing factors of decubitus ulcer by measuring the pressure changes while controlling the air of the cushion and correcting the seating posture ...
KEY FINDING: In Case 1, adjusting the air in the cushion increased the contact area and decreased the average pressure on the buttocks.
Spinal Cord Series and Cases, 2019 • February 22, 2019
This case series reviews the use of proximal femoral resection and pedicled Tensor Fascia Lata (TFL) flap in managing infected deep trochanteric ulcers communicating with the hip joint in three patien...
KEY FINDING: Proximal femoral resection with pedicled TFL muscle flap is an effective procedure for covering difficult trochanteric pressure ulcers that involve the hip joint.
PLoS ONE, 2019 • February 13, 2019
The objective of this study was to monitor the weight shift activity of full-time wheelchair users with acute spinal cord injury over multiple epochs of time in order to determine consistency or routi...
KEY FINDING: No consistent pattern of activity changes emerged across all in-seat activity metrics.
Top Spinal Cord Inj Rehabil, 2019 • January 1, 2019
This study examined protective factors against pressure injuries in socioeconomically disadvantaged adults with SCI using a qualitative analysis of treatment notes from a pressure injury prevention in...
KEY FINDING: Eight types of potentially protective factors were identified: meaningful activity, motivation to prevent negative health outcomes, stability/resources, equipment, communication and self-advocacy skills, personal traits, physical factors, and behaviors/activities.
Turk J Phys Med Rehab, 2017 • November 27, 2017
This study investigated the use of Lucilia sericata larvae in treating decubitus ulcers resistant to conventional therapies. 36 patients with decubitus ulcers were treated with Lucilia sericata maggot...
KEY FINDING: Twenty nine lesions (78.9%) were Grade 2 and 3 and were completely healed after four to eight treatment sessions.
Turk J Phys Med Rehab, 2018 • November 5, 2018
This study aimed to evaluate the recurrence rate of pressure ulcers (PU) after reconstruction in patients with spinal cord injury (SCI) who were treated by a combined team of plastic surgeons and phys...
KEY FINDING: The study found a PU recurrence rate of 23.1% in patients with SCI after reconstruction, with sacral ulcers being the most common site of recurrence (82.1%), followed by ischial (20.5%) and trochanteric ulcers (15.4%).
Spinal Cord Series and Cases, 2019 • February 21, 2019
The treatment of PI stage III and IV in patients with SCI included input from plastic surgery, rehabilitation medicine, nursing and other involved professions. The cost course of PI treatment in patie...
KEY FINDING: Treatment for severe PIs in SCI patients involves several medical areas like plastic surgery, rehabilitation, and nursing.