Browse the latest research summaries in the field of endocrinology for spinal cord injury patients and caregivers.
Showing 81-90 of 211 results
Top Spinal Cord Inj Rehabil, 2021 • January 1, 2021
Persons with SCI are at high risk for developing neurogenic obesity due to muscle paralysis and obligatory sarcopenia, sympathetic blunting, anabolic deficiency, and blunted satiety. Upper limb utiliz...
KEY FINDING: Obesity and increased weight are significant contributors to upper extremity overuse injuries in persons with SCI.
PLOS ONE, 2023 • March 3, 2023
This study protocol describes an overview of systematic reviews based on network meta-analysis, focusing on the safety and efficacy of different anti-hyperglycemic agents for patients with T2DM. The p...
KEY FINDING: The overview aims to assess the methodological quality of published network analyses in the field of T2DM anti-hyperglycemic agents.
J. Pers. Med., 2022 • December 7, 2022
This article reviews the existing literature on nutrition, dietary intake, and nutrition education in persons with SCI as it relates to metabolic dysfunction. Nutrition education topics are presented ...
KEY FINDING: Persons with SCI often have poor dietary intakes, not meeting recommended guidelines for fruits, vegetables, and whole grains.
Neurotrauma Reports, 2021 • January 1, 2021
This retrospective cohort study examined the potential effects on outcomes of hyperglycemia in the hyperacute stage after acute traumatic SCI. Hyperglycemia diagnosed at day 7 post-injury was associat...
KEY FINDING: Hyperglycemia at day 7 post-injury was associated with significantly greater mortality rates within the first year after acute traumatic SCI.
Frontiers in Physiology, 2021 • February 3, 2021
This study investigated the impact of paraplegia on dietary fat absorption by tracking the time course of exogenous fatty acid incorporation into the plasma triacylglycerol (TAG) pool in the postprand...
KEY FINDING: The study found no significant main effect of group (PARA vs. CON) on exogenous TAG, suggesting that the overall amount of fat absorbed wasn't significantly different.
J Phys Med Rehabil, 2020 • March 27, 2020
Spinal cord injury (SCI) leads to changes in body composition, specifically an obligatory sarcopenia, which contributes to a significant decrease in total daily energy expenditure (TDEE) and an accumu...
KEY FINDING: Equations developed for able-bodied individuals inaccurately assess energy expenditure for those with SCI.
The Journal of Spinal Cord Medicine, 2020 • October 2, 2020
This systematic review aimed to evaluate melatonin levels in individuals with complete cervical SCI compared to healthy controls and those with other types of SCI. The review analyzed 12 studies to as...
KEY FINDING: Adults with complete cervical SCI tend to have absent diurnal melatonin rhythms compared to healthy controls and individuals with thoracolumbar SCI below T3.
The Journal of Spinal Cord Medicine, 2015 • January 1, 2015
This study investigated the retention of favorable changes in lean tissue mass (LTM) and resting energy expenditure (REE) after discontinuation of testosterone replacement therapy (TRT) in hypogonadal...
KEY FINDING: Significant increase in LTM was observed from baseline to TRT-12M (50.2 ± 7.4 vs. 52.9 ± 6.8 kg, P < 0.01), which persisted Post-TRT compared to BL (52.2 ± 7.8 kg, P < 0.05).
Osteoporos Int, 2014 • November 1, 2014
The study explored the association between adiponectin levels and bone strength in paralyzed men with spinal cord injury, finding an inverse relationship between bone strength and circulating adiponec...
KEY FINDING: Axial stiffness and maximal load were inversely associated with circulating adiponectin levels after adjusting for injury duration and lower extremity lean mass.
The Journal of Spinal Cord Medicine, 2015 • January 1, 2015
This review discusses the use of neuromuscular electrical stimulation (NMES) or functional electrical stimulation (FES) to improve body composition and metabolic profile after SCI. NMES and FES traini...
KEY FINDING: Electrical stimulation, including NMES and FES, can increase muscle size in paralyzed lower extremities after SCI.