Endocrinology Research

KEY FINDING: Excess weight leads to physical health conditions such as chronic diseases and SCI secondary complications.

KEY FINDING: AdipoRon alleviated mechanical nociception in spared nerve injury (SNI) mice, indicating a reduction in pain sensitivity.

KEY FINDING: RMR is 9% greater than BMR in persons with SCI.

KEY FINDING: After 26 weeks of semaglutide administration, total body weight, fat tissue mass, total body fat percent, and visceral adipose tissue volume decreased.

KEY FINDING: The probability of developing NAFLD increases as BMI increases in both SCI and Non-SCI cohorts.

KEY FINDING: SCI involves both primary injury, which is often irreversible, and secondary injury, which can be delayed and potentially treatable. Understanding the pathophysiology of secondary damage is crucial for timely specialist intervention.

KEY FINDING: The study found that 46.1% of the subjects had overt sarcopenia, and 10.1% had severe sarcopenia. Patients with severe sarcopenia had significantly lower BMI and MNA values.

KEY FINDING: Dysregulation of bone remodeling impairs immune cell function, leading to immune evasion and promoting tumor cell survival and growth in the bone.

KEY FINDING: Existing evidence suggested that NMES effectively improves glycemic control predominantly in middle-aged and elderly population with type 2 diabetes, obesity, and spinal cord injury.

KEY FINDING: Glucose levels were significantly higher in individuals with SCI compared to those without SCI at 60 and 120 minutes after an oral glucose tolerance test (OGTT).