Gastroenterology Research

KEY FINDING: Spinal cord injury resulted in abnormal morphology of interstitial cells of Cajal (ICCs) in the colon tissues of rats.

KEY FINDING: The primary outcomes measured will be bowel function recovery and patient satisfaction. Secondary outcomes will include quality of life, assessed using the SF-36 questionnaire, which covers aspects like physical pain and mental health.

KEY FINDING: The study found a significant decrease in the mean NBD score after three months of using Navina Smart, indicating improved bowel function.

KEY FINDING: There was a small amount of literature in SCI, there was little to no literature available for MS.

KEY FINDING: Fecal microbiota transplantation (FMT) improved locomotor recovery in SCI mice, as indicated by increased BMS scores and improved gait parameters.

KEY FINDING: The MENTOR tool showed acceptable concordance with physician decisions regarding treatment adequacy and the need for treatment change.

KEY FINDING: Fecal transplant from uninjured donor rats with increased anxiety-like behaviour was not only ineffective in preventing injury-induced microbiota changes, but it also increased intestinal permeability and anxiety-like behaviour of the recipient rats.

KEY FINDING: A basic bowel management (BBM) program should be used for both reflexic and areflexic NBD.

KEY FINDING: The review found that alpha diversity in chronic SCI patients might be lower compared to healthy controls, while alpha diversity in MS patients might be similar or lower.

KEY FINDING: There was an increase in the frequency of bowel movements and a decrease in the frequency of fecal incontinence from admission to discharge.