Immunology Research
Browse the latest research summaries in the field of immunology for spinal cord injury patients and caregivers.
Showing 241-250 of 730 results
Incidence and Risk Factors for Pneumonia in the Chronic Phase of Cervical Spinal Cord Injury with Complete Motor Paralysis
Spine Surg Relat Res, 2023 • January 17, 2023
This retrospective study examined the incidence and risk factors for pneumonia in patients with cervical spinal cord injury (CSCI) and complete motor paralysis. The study found that pneumonia occurred...
KEY FINDING: Pneumonia occurred in 36% of patients throughout the study period and in 20% after 30 days of hospitalization.
Prevalence of Antibiotic Allergy at a Spinal Cord Injury Center
Fed Pract, 2023 • May 19, 2023
This retrospective study evaluated the frequency and characteristics of antibiotic allergies at a single SCI center. In this study, we evaluated the frequency and characteristics of antibiotic allergi...
KEY FINDING: Almost 30% of patients with SCI had a recorded allergy to at least 1 antibiotic. Almost 30% of patients with SCI had a recorded allergy to at least 1 antibiotic.
Management of Asymptomatic Bacteriuria and Urinary Tract Infections in Patients With Neurogenic Bladder and Factors Associated With Inappropriate Diagnosis and Treatment
Arch Phys Med Rehabil, 2024 • January 1, 2024
This multicenter study evaluated the appropriateness of ASB and UTI management in patients with NB. It identified factors associated with inappropriate diagnosis and treatment to improve the quality o...
KEY FINDING: Nearly all ASB encounters had appropriate diagnosis (98%).
Urinary tract infections and intermittent catheterization among patients with spinal cord injury in Chinese community
Scientific Reports, 2023 • October 11, 2023
This study aimed to understand the status of UTIs and bladder management in Chinese community-based SCI patients. The findings indicate a higher prevalence of UTIs in this population compared to devel...
KEY FINDING: The prevalence of UTIs in Chinese community SCI patients was 72.9%, higher than reported in developed countries.
Perceptions, experiences, and beliefs regarding urinary tract infections in patients with neurogenic bladder: A qualitative study
PLOS ONE, 2023 • November 1, 2023
This qualitative study explored the perceptions, experiences, and beliefs regarding urinary tract infections (UTIs) in patients with neurogenic bladder (NB). It involved virtual focus groups with 23 V...
KEY FINDING: Caregivers play a crucial role in UTI management by enabling access to care, helping recognize symptoms, and aiding in understanding medical information.
Prevalence of Multidrug-Resistant and ESBL-Producing Bacterial Pathogens in Patients with Chronic Wound Infections and Spinal Cord Injury Admitted to a Tertiary Care Rehabilitation Hospital
Antibiotics, 2023 • November 2, 2023
This retrospective study evaluated the prevalence of bacterial pathogens, particularly MDR and ESBL-producing bacteria, in pressure ulcers of spinal cord injury patients. The study found that S. aureu...
KEY FINDING: Staphylococcus aureus was the most commonly isolated organism from ulcers, especially in sacral and gluteal regions.
Increase in Serum Interleukin-1 Receptor Antagonist (IL-1ra) Levels after Wheelchair Half Marathon Race in Male Athletes with Spinal Cord Injury
J. Clin. Med., 2023 • November 15, 2023
This study investigates the impact of a wheelchair half marathon on the immune response of athletes with cervical (CSCI) and thoracic/lumber (SCI) spinal cord injuries, focusing on interleukin-1 recep...
KEY FINDING: IL-1ra levels were higher in SCI participants immediately after the race compared to CSCI participants. Additionally, IL-1ra increased in both groups one hour after the race.
The presence of Candida parapsilosis with intrathecal baclofen pump in a person with high cervical spinal cord injury; infection or colonization? A Case Report
Spinal Cord Series and Cases, 2023 • October 23, 2023
This case report presents the instance of a patient with a spinal cord injury developing an ITB pump infection involving Candida parapsilosis. The case highlights the diagnostic challenges in distingu...
KEY FINDING: A patient with SCI and an ITB pump developed a pump pocket infection with methicillin-sensitive Staphylococcus aureus, diphtheroids, and Candida parapsilosis.
Factors associated with urinary tract infection in the early phase after performing intermittent catheterization in individuals with spinal cord injury: a retrospective study
Frontiers in Medicine, 2023 • November 17, 2023
This retrospective study aimed to investigate the occurrence rate of urinary tract infections (UTIs) in the early phase after performing intermittent catheterization (IC) and to explore the possible f...
KEY FINDING: UTI after performing IC is prevalent among people with SCI.
Patients with Chronic Spinal Cord Injury Display a Progressive Alteration over the Years of the Activation Stages of the T Lymphocyte Compartment
Int. J. Mol. Sci., 2023 • December 18, 2023
This study investigated the alteration of T lymphocytes in patients with chronic SCI over different years of evolution, revealing a progressive damage to the circulating T lymphocyte compartment. The ...
KEY FINDING: Chronic SCI patients show a significant reduction in circulating CD4+ and CD8+ T lymphocytes compared to healthy controls.