Browse the latest research summaries in the field of medical imaging for spinal cord injury patients and caregivers.
Showing 151-160 of 201 results
Neural Regeneration Research, 2013 • December 1, 2013
This study investigated the use of diffusion tensor imaging (DTI) to quantitatively measure pathological changes in a rat model of chronic cervical spondylotic myelopathy. A novel spongy polyurethane ...
KEY FINDING: The fractional anisotropy value gradually decreased over time (4 hours to 1 week) after spinal cord injury in the rat model.
Biology of the Cell, 2025 • March 4, 2025
This study introduces a novel method, the fingerprint enhancement (FP-E) algorithm, for analyzing undergrowth collagen fibers, particularly in the context of spinal cord injury (SCI). The FP-E method ...
KEY FINDING: The fingerprint enhancement (FP-E) algorithm effectively detects and characterizes undergrowth collagen fibers in spinal cord injury samples.
J Neurosci Methods, 2016 • September 15, 2016
The study introduces retroDISCO, a novel optical clearing technique for intact mouse spinal cords, enabling efficient and accurate quantification of retrograde labeled motor neurons using confocal mic...
KEY FINDING: Complete optical clearing of spinal cords using retroDISCO takes approximately four hours. Confocal microscopy can then obtain z-stacks of labeled motor neuron pools within 3–5 minutes.
PLoS ONE, 2014 • October 3, 2014
This study uses Autofluorescent Flavoprotein Imaging (AFI) to examine changes in spinal dorsal horn metabolic activity in a rat model of nerve-injury induced pain (Seltzer model) and the effect of spi...
KEY FINDING: Neuropathic rats demonstrated an AFI-response to palpation, while naı¨ve rats did not.
Indian Journal of Radiology and Imaging, 2011 • August 1, 2011
This study investigates the feasibility of spinal tractography and fractional anisotropy (FA) value comparison in spinal cord injury patients versus a control group. DTI was performed on 29 subjects (...
KEY FINDING: The mean FA value was 0.550±0.09 in the control group and 0.367±0.14 in the patients; this difference was statistically significant (P=0.001).
Biomedical Optics Express, 2022 • May 1, 2022
The study introduces a multi-wavelength photoacoustic time-frequency spectral analysis (MWPA-TFSA) method for simultaneous detection of changes in bone minerals, lipids, and bone marrow cluster size, ...
KEY FINDING: Osteoporotic bones exhibit a lower content ratio of hemoglobin (Hb) to lipid compared to normal bones, as indicated by the lower energy ratio of E760/E930 in MWPA measurements.
Spinal Cord, 2017 • July 1, 2017
This study demonstrated a negative correlation between damaged cord ratios and both walking ability and plantarflexion torque output in participants with iSCI. These findings suggest that axial spinal...
KEY FINDING: Damage ratios were negatively correlated with distance walked in 6 minutes, average daily strides, and maximum plantarflexion torque.
Genome Biology, 2024 • March 8, 2024
SpaDo is introduced as a computational framework for multi-slice spatial domain analysis, including multi-slice spatial domain detection, reference-based spatial domain annotation, and multi-slice clu...
KEY FINDING: SpaDo demonstrates good interpretability, robustness, and tolerance to noise and batch effects in spatial transcriptomic data analysis.
Photoacoustics, 2021 • August 26, 2021
This study investigates the feasibility of using multi-wavelength photoacoustic (MWPA) analysis to detect collagen in bone as a biomarker for bone health assessment, focusing on the wavelength range o...
KEY FINDING: The study successfully demonstrated the feasibility of using multi-wavelength photoacoustic (MWPA) analysis for detecting collagen content in bone.
eNeuro, 2025 • January 1, 2025
This study demonstrates that norepinephrine axons in the adult mouse brain are capable of regrowth following injury induced by the neurotoxin DSP4, challenging the widely held belief that axons in the...
KEY FINDING: Norepinephrine axons in the adult mouse brain can regrow following injury induced by DSP4.