Browse the latest research summaries in the field of medical imaging for spinal cord injury patients and caregivers.
Showing 71-80 of 201 results
Neural Plasticity, 2021 • April 13, 2021
This study investigates the effect of LIFU on neuropathic pain (NP) and the expression of potassium chloride cotransporter 2 (KCC2) in the spinal cords of rats with peripheral nerve injury (PNI). The ...
KEY FINDING: LIFU stimulation alleviated mechanical allodynia in PNI model rats, as indicated by increased PWT50 values after 3 weeks of LIFU treatment compared to the LIFU− group.
Spinal Cord, 2021 • October 6, 2020
This retrospective study assessed whether axial damage ratios from MRIs could predict walking ability one year after spinal cord injury (SCI). The study found that axial damage ratios were significant...
KEY FINDING: Axial damage ratios from MRIs taken early after injury were significant predictors of walking ability one year post-SCI; smaller ratios correlated with a higher likelihood of walking.
The Journal of Spinal Cord Medicine, 2020 • January 1, 2020
Skeletal muscle mitochondrial activity is reduced by ∼50–60% after SCI, resulting in impaired energy expenditure, glucose utilization and insulin sensitivity. Near infra-red spectroscopy (NIRS) is a n...
KEY FINDING: Only four participants produced data with accepted rate constants of 0.002–0.013 s−1 and r2 of 0.71–0.87.
Asian Spine Journal, 2020 • December 1, 2020
This prospective study evaluated trunk musculature and intervertebral discs in SCI patients with thoracolumbar fractures using MRI. The study revealed significant decreases in disc and trunk parameter...
KEY FINDING: Significant decreases were observed in disc parameters (disc angle, skin angle, CSA, disc height) and trunk parameters (trunk width, trunk depth, CSA of lumbar muscles) during the first 3 months after SCI.
J. Clin. Med., 2023 • December 23, 2022
The study assessed TSPO expression as an indicator of microglial activation using (R)-[11C]PK11195 PET imaging in a rat SCI model. Clinical application of (R)-[11C]PK11195 PET/MRI in patients with NeP...
KEY FINDING: TSPO is mainly expressed in activated microglia in the injured spinal cord.
NeuroImage: Clinical, 2023 • February 1, 2023
This study tracked the spatiotemporal dynamics of remote anterograde and retrograde spinal tract degeneration in the upper cervical cord following SCI over two years utilizing quantitative MRI. Linear...
KEY FINDING: Retrograde neurodegeneration in the CST develops over time, forming a gradient towards lower cervical levels, particularly in tetraplegics.
Brain Imaging Behav, 2020 • June 1, 2020
This study introduces a novel method using dMRI tractography to delineate the CST and isolate its hand motor representation (HMFTs). The study quantifies the variability of these tracts in 37 healthy ...
KEY FINDING: The study successfully delineated the CST and HMFTs using a novel dMRI tractography method.
Neurosurgery, 2021 • September 1, 2021
This review explores the potential of ultrasound technology for diagnostic and therapeutic interventions in traumatic spinal cord injury (SCI). The authors discuss the fundamentals of ultrasound, incl...
KEY FINDING: Ultrasound can enable real-time In Vivo spinal cord monitoring with high spatiotemporal resolution, overcoming limitations of existing modalities.
The Journal of Spinal Cord Medicine, 2016 • May 1, 2016
The study investigated the efficacy of using ultrasonography to measure rectal diameter and area as an additional parameter for evaluating neurogenic bowel in patients with spinal cord injury (SCI). T...
KEY FINDING: After defecation, the UMNB group had significantly smaller rectal diameters and areas compared to the LMNB group.
JOURNAL OF NEUROTRAUMA, 2017 • February 1, 2017
The study assessed brain activation during ankle movement in individuals with incomplete SCI compared to healthy controls using fMRI. Results showed that individuals with incomplete SCI exhibited incr...
KEY FINDING: Individuals with incomplete SCI showed increased brain sensorimotor activation during voluntary movement compared to healthy controls.