Browse the latest research summaries in the field of neurology for spinal cord injury patients and caregivers.
Showing 131-140 of 5,253 results
bioRxiv preprint, 2023 • July 3, 2023
The study investigates the effects of Dynamic Stimulation (DS) on corticospinal motor responses using a corticospinal platform in rats. The platform allows for selective cortical stimulation and simul...
KEY FINDING: Dynamic Stimulation (DS) selectively increases the excitability of spinal interneurons that first process corticospinal input, without altering the magnitude of commands from the motor cortex.
Spinal Cord, 2023 • July 19, 2023
This paper describes the details of a complex intervention administered as part of a large randomised controlled trial. It will facilitate the subsequent interpretation of the trial results and enable...
KEY FINDING: A detailed intervention manual has been developed to help standardise the delivery of the intervention.
Acta Neurochirurgica, 2023 • July 21, 2023
The case report describes a unique complication of intrathecal baclofen (ITB) therapy where a curled-up silicone layer around the sutureless pump connector led to system malfunction and CSF leakage. T...
KEY FINDING: A novel form of catheter malconnection was identified, involving the curling of the silicone layer surrounding the sutureless pump connector in an intrathecal baclofen (ITB) system.
Frontiers in Neuroscience, 2023 • July 7, 2023
This study investigates the impact of targeted transcutaneous spinal cord stimulation (tSCS) combined with activity-based training on upper limb function in individuals with motor-complete spinal cord...
KEY FINDING: Targeted tSCS, along with weekly activity-based training, significantly increased muscle activity and strength in specific upper-limb muscles in individuals with motor-complete cervical SCI.
Frontiers in Molecular Neuroscience, 2023 • July 10, 2023
This review describes the changes in IL-10 and its receptors after spinal cord injury. It further elucidates the multiple neuroprotective effects and underlying mechanisms of IL-10 in the treatment of...
KEY FINDING: IL-10 exhibits anti-oxidative stress effects by enhancing mitochondrial homeostasis, decreasing lipid peroxidation, and inhibiting the production of peroxides and inflammatory cytokines after SCI.
medRxiv preprint, 2023 • July 23, 2023
This study aimed to determine if transcutaneous spinal cord stimulation improves autonomic regulation after spinal cord injury (SCI). The results indicated that spinal cord stimulation does not improv...
KEY FINDING: Transcutaneous spinal cord stimulation generates tonic, frequency-dependent sympathetic activation below the level of injury.
Frontiers in Neurology, 2023 • July 12, 2023
This study investigated the acceptability, usability, and feasibility of the Experience Sampling Method (ESM) in patients with chronic secondary neuropathic and musculoskeletal pain syndromes. The stu...
KEY FINDING: The general evaluation showed no significant influence of ESM on participants’ social contacts, activities, or mood.
Scientific Reports, 2023 • August 4, 2023
This study investigated the effects of spinal cord epidural stimulation (scES) at the L3 level on bladder and external urethral sphincter (EUS) function in both intact and spinal cord injured (SCI) ra...
KEY FINDING: L3 scES at select frequencies and intensities of stimulation produced a reduction in void volumes and EUS burst duration in intact rats.
Life, 2023 • July 14, 2023
This study investigated the effects of transcutaneous spinal cord stimulation (scTS) on respiratory function in post-acute COVID-19 patients and healthy controls. The results showed that scTS improved...
KEY FINDING: In COVID-19 patients, scTS significantly increased peak inspiratory flow (PIF) and peak expiratory flow (PEF).
Cureus, 2023 • June 29, 2023
This case report describes a rare presentation of Postural Orthostatic Tachycardia Syndrome (POTS) in a young female patient with a traumatic spinal cord injury (SCI). The patient developed POTS durin...
KEY FINDING: The patient experienced a significant increase in heart rate (35-40 bpm) upon tilting, without a drop in blood pressure, leading to the diagnosis of POTS after excluding other potential causes of tachycardia and syncope.