Neuroplasticity Research

KEY FINDING: Lampreys express four main types of lecticans (A, B, C, and D), which are found in both glial cells and neurons.

KEY FINDING: Increased metabolism was observed in the supplementary motor areas, comprehension centers, parts of the parietal and temporal lobes, putamen, and cerebellum in SCI patients.

KEY FINDING: Three-minute stimulation with iTBS/tsDCS significantly increased MEP after week 2 and week 4 treatments.

KEY FINDING: Rats in the G-CSF/exercise group showed the most effective functional recovery based on the BBB scale and inclined plane test results.

KEY FINDING: Repeated transspinal stimulation reduced soleus H-reflex excitability in both motor incomplete and complete SCI, but not in healthy control subjects.

KEY FINDING: The activity-dependent increase in KCC2 functionally contributes to H-reflex recovery after spinal cord injury.

KEY FINDING: Brain reorganization after SCI involves changes in the somatosensory and motor cortices, including the expansion of facial representation into areas formerly representing the affected limbs.

KEY FINDING: The amplitude of corticospinal responses and the magnitude of maximal voluntary contractions in targeted muscles increased after PCMS combined or not with exercise, but not after sham-PCMS combined with exercise.

KEY FINDING: Spinal cord ES was initially explored to target axons that were damaged after SCI in order to bias the direction and possibly extent of neurite outgrowth, suggesting that spinal cord direct current ES creates a relatively static EF.

KEY FINDING: MMS rehabilitation significantly increased the number of pellets taken at 13 and 14 weeks PI in rats with chronic cervical SCI, indicating an improvement in forelimb function.