Browse the latest research summaries in the field of physiology for spinal cord injury patients and caregivers.
Showing 1-10 of 292 results
Neuromodulation, 2023 • July 1, 2023
This study investigates the spatiotemporal distribution of spinal ECAPs during SCS in sheep, examining how these ECAPs relate to lower extremity motor responses. The researchers found that spinal ECAP...
KEY FINDING: Distinct regions of lateral stimulation resulted in simultaneously increased ECAP and EMG responses compared to stimulation at adjacent lateral contacts.
Frontiers in Neurology, 2023 • June 2, 2023
This study examined the changes in corticospinal excitability (CSE) of the primary motor cortex (M1) hand area after spinal cord injury (SCI) and its correlation with motor function and activities of ...
KEY FINDING: The CSE of the dominant hemisphere M1 hand area decreased in SCI patients.
bioRxiv preprint, 2023 • July 3, 2023
The study investigates the effects of Dynamic Stimulation (DS) on corticospinal motor responses using a corticospinal platform in rats. The platform allows for selective cortical stimulation and simul...
KEY FINDING: Dynamic Stimulation (DS) selectively increases the excitability of spinal interneurons that first process corticospinal input, without altering the magnitude of commands from the motor cortex.
Front. Rehabil. Sci., 2023 • July 26, 2023
This study evaluated the acute cardiovascular effects of a 20-min session of high PAS on 17 healthy individuals by measuring heart rate variability (HRV). The results showed a transient increase in pa...
KEY FINDING: A significant decrease in low-frequency (LF) power and low-frequency to high-frequency (HF) ratio was observed during stimulation, indicating increased parasympathetic activity.
FUNCTION, 2023 • June 13, 2023
The study investigated the influence of genetics, age, and sex on respiratory motor plasticity induced by AIHH in healthy adults. Results showed that the APOE4 genotype, sex, and age are significant d...
KEY FINDING: Individuals heterozygous for APOE4 showed lower AIHH-induced changes in diaphragm MEP amplitudes.
bioRxiv preprint, 2023 • August 4, 2023
This study investigates the role of Nox4 in reduced muscle specific force after spinal cord injury (SCI) using a conditional knockout mouse model. The results suggest a link between Nox4 expression in...
KEY FINDING: Peak twitch force in control mice after SCI was reduced by 42% compared to sham-operated controls.
J. Funct. Morphol. Kinesiol., 2023 • August 21, 2023
The study compared glucose tolerance biomarkers among people with and without SCI, finding that individuals with SCI are more glucose intolerant compared to people without SCI. It also compared glucos...
KEY FINDING: Glucose levels were significantly higher in individuals with SCI compared to those without SCI at 60 and 120 minutes after an oral glucose tolerance test (OGTT).
Biomedicines, 2023 • September 22, 2023
This study aimed to investigate the relationships between the different levels and degrees of incomplete spinal cord injury (iSCI) evaluated with magnetic resonance imaging (MRI) and the results of no...
KEY FINDING: The study revealed consistent positive correlations in iSCI patients between the bilateral decrease of the spinal half injury MRI scores and a decrease of the transcranially-evoked MEP amplitudes.
Scientific Reports, 2023 • December 6, 2023
This study examined upper limb motor pool recruitment patterns using transcutaneous spinal stimulation (TSS) in individuals with tetraplegia following cervical spinal cord injury (SCI). TSS was delive...
KEY FINDING: Responses in muscles below the injury were less sensitive to TSS compared to those above the lesion.
J. Clin. Med., 2024 • February 2, 2024
This study investigated the prevalence and associations of sarcopenia in patients with spinal cord injury (SCI). The research found significant associations between sarcopenia and gender, age, and the...
KEY FINDING: Women with SCI are more likely to develop sarcopenia than men.